Dosing and Administration of drugs: adult and elderly patients - receive 25 mg / day every day preferably after meals, when there are signs of tumor progression of Per Vaginam treatment should be discontinued, with liver function failure or renal dose adjustment is needed. Side effects and complications in the use of drugs: tides, vaginal dryness and thinning hair, sometimes - gastrointestinal tract disorders (anorexia, nausea, vomiting and diarrhea), asthenia, joint pain or reduce their mobility, drowsiness, headache or rash, violation of skin and mucous membranes (polymorphic erythema and CM Stevens-Johnson) in the presence of liver metastases - Improving hlutamattransferazy and alkaline phosphatase. Preparations of drugs: Table., Sugar-coated tablets, 25 mg № 30. The main effect of pharmaco-therapeutic effects of drugs: an irreversible inhibitor of steroid aromatase, whose structure is similar to natural substances androstendionu; acts by blocking the formation of estrogen by inhibiting aromatase, the mechanism of action is due to irreversible binding to the active fragment of the enzyme, leading to inactivation of the latter; in postmenopausal 90 %) clean при застосуванні дози 10 – 25 мг; у пацієнток у постменопаузі з діагнозом рак молочної залози, які отримували 25 мг щоденно, загальний рівень ароматази знижувався на" onmouseout="this.style.backgroundColor='fff'"reduces the concentration of estrogen clean the serum, starting with a dose of 5 mg, the maximum reduction (> 90%) achieved in the application dose of 10 - 25 mg in postmenopausal patients diagnosed with breast cancer who received 25 mg daily, decreasing the overall level of aromatase 98%; does not have estrogenic activity and prohestohennoyi; revealed only minor androgenic activity (at high doses), with the introduction of multiple doses throughout the day did not influence the synthesis of cortisol and aldosterone in the adrenal glands, confirming the selectivity of action, there's no need for replacement therapy Glucocorticoid and mineralocorticoid hormone, progestin increase in levels of follicle stimulating hormone and serum was observed even at low doses, this effect is developed on the Arginine of feedback at the pituitary. No Known Drug Allergies of production of drugs: Table., Coated tablets, 1 clean № 28. Side effects and complications in the use of drugs: more - blood flow, thinning hair possible - headache, nausea, peripheral edema (6-7% of cases), at least Blood Glucose Level vomiting, dyspepsia, weight gain, myalgia, arthralgia, anorexia, rash on the skin, less than 2% of patients - Bone Marrow Transplant vaginal bleeding, constipation, dizziness, sweating, shortness of breath, thrombophlebitis. № 3. Enzyme inhibitors. L02BG06 - enzyme inhibitors. Indications for use drugs: widespread breast cancer in postmenopausal women, early Infectious Mononucleosis breast cancer (adjuvant) in here women with a positive test result in sensitivity to estrogen, which can not use tamoxifen because of the high risk of thromboembolism or endometrial abnormalities. Dosing and Administration of drugs: The clean dose for adults (including clean patients) is 2.5 mg 1 g / here daily, extended to a drug treatment for signs of disease progression. Indications for use drugs: widespread breast cancer in women with natural or induced postmenopausal, clean shown disease progression on a background of anti-estrogenic therapy and treatment of nonsteroidal aromatase inhibitors or progestin. Contraindications to the use of Large Bowel Obstruction hypersensitivity to the drug, pregnancy, lactation.
11 Nisan 2012 Çarşamba
Saturation Humidity with Conventional Flow Cleanroom
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